![]() Sable shares his biggest hopes for the fertility field and what entrepreneurs need to do to get it to the next level.ĭr. From lessons from oncology to bottlenecks holding us back, Dr. They discuss what it is going to take to scale to a million cycles in the US and 15 million around the world. ![]() David Sable, a retired REI and current serial investor in biotechnology and other companies that aim to make the field more efficient and accessible by the patients we aim to treat. On this episode of Inside Reproductive Health, Griffin talks to Dr. Venture Capital has been slowly making its way into the field over the last several years. Get six of our favorite Motherboard stories every day by signing up for our newsletter. He has plans to bring something similar to Montreal, Toronto and Vancouver. The Calgary clinic-which is a walk-in, with no referral necessary-is the first stand-alone IVC clinic in the world, said Broome. And anyone looking to do genetic testing on their embryos won't get that through this budget clinic. Women at risk of overstimulating, such as those with polycystic ovaries, may not want to do their cycles without careful monitoring. Couples who need intracytoplasmic sperm injection (ICSI) for problem sperm, for instance, won't benefit. There were 11 successful pregnancies in the IVC group and 12 in the IVF group. Rates of fertilization, pregnancy and live birth were all similar between the groups, they reported last April in the Journal of Assisted Reproduction and Genetics, although classic IVF produced more high-quality embryos. Broome, along with Kevin Doody and Kathleen Doody, who are fertility doctors at the Center for Assisted Reproduction in Bedford, Texas, randomly assigned 40 women to receive either IVF or IVC, and placed up to 10 eggs into either an INVOcell or an incubator. Broome called it "digital healthcare"-something not common in Canadian fertility medicine.įor all the differences, though, ultimate success rates appear to be about the same. ![]() The clinic places a premium on accessible communications, with payments, appointment bookings, reminders and medical records available online. Read More: An Egg Freezing 'Pop-Up Store' Appears in London The INVOcell will remain in place for five days after that, meaning that embryos are transferred to the uterus on either a Monday, a Tuesday or a Wednesday the following week. For instance, all day 10 ultrasounds will happen on a Monday, said Broome, and based on how the eggs are developing on that day, the egg retrieval will be scheduled for either Wednesday, Thursday or Friday that same week. Other protocols make it possible for the clinic to close on weekends-which also saves money. These are complex and expensive operations when handled by a mechanical incubator, but "effortless" when managed in-house, according to Broome. She also keeps the temperature even and filters out toxins with her liver and kidneys. Made of polystyrene (just like petri dishes), it is gas-permeable, so appropriate levels of carbon dioxide and oxygen can be maintained inside it by the woman's own body. The 4cm-by-3cm capsule, called an INVOcell, is about the size and shape of an old photographic film canister. In IVC, all of that takes place inside a woman's body-specifically, inside a little plastic capsule tucked inside her vagina. In classic IVF, that happens outside the body. The most obvious is where fertilization and early embryo development take place. Conventional IVF and this newer variant-called intravaginal culture, or IVC-both involve stimulating the ovaries to produce extra eggs, removing the eggs surgically, putting sperm and eggs together artificially and placing nicely-developed embryos into the uterus.īut there are some key differences.
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